⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559639 | 0.89 | — | — | |
| SCHEMBL8556094 | 0.88 | KDM4E (0.33) | — | |
| SCHEMBL8559801 | 0.81 | SLC6A2 (0.35) | — | |
| SCHEMBL8556088 | 0.74 | KDM4E (0.33) | — | |
| SCHEMBL335247 | 0.74 | GSK3B (0.41) | — | |
| SCHEMBL8559526 | 0.73 | CAMK2B (0.34) | — | |
| Ammonia Solution, Strong SCHEMBL28389634 | 0.73 | GSK3B (0.39) | — | |
| SCHEMBL8559795 | 0.72 | KDM4E (0.32) | — | |
| SCHEMBL8558961 | 0.72 | SLC6A2 (0.32) | — | |
| SCHEMBL1234203 | 0.70 | GSK3B (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575954-B1 | Aminoalkylcarbamic esters of eseroline suitable for use as cholinesterase acitivity inhibitors and relative preparation process | MEDIOLANUM FARMACEUTICI SRL (IT) | 1998-09-02 | — | — | EP | disclosed |