Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.73 |
| ▸ | DRD2 | P14416 | 1/20 | 0.73 |
| ▸ | HTR6 | P50406 | 1/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | MAOB | P27338 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1463660 | 0.97 | HTR1A (0.69) | HTR1ADRD2HTR6MEN1KMT2A | |
| SCHEMBL8559706 | 0.95 | HTR1A (0.69) | HTR1ADRD2HTR6MEN1KMT2A | |
| SCHEMBL8559095 | 0.95 | HTR1A (0.69) | HTR1ADRD2HTR6MEN1KMT2A | |
| SCHEMBL1703636 | 0.95 | HTR1A (0.69) | HTR1ADRD2HTR6MEN1KMT2A | |
| SCHEMBL8554700 | 0.95 | HTR1A (0.69) | HTR1ADRD2HTR6MEN1KMT2A | |
| SCHEMBL8559799 | 0.95 | HTR1A (0.69) | HTR1ADRD2HTR6MEN1KMT2A | |
| SCHEMBL8556230 | 0.92 | GRM5 (0.66) | HTR1ADRD2HTR6MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL27657032 | 0.90 | GRM5 (0.64) | HTR1ADRD2HTR6MEN1KMT2A | |
| SCHEMBL13469510 | 0.88 | HTR1A (0.79) | HTR1ADRD2MAOB | |
| SCHEMBL6275178 | 0.87 | KDM4E (0.69) | HTR1ADRD2HTR6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575954-B1 | Aminoalkylcarbamic esters of eseroline suitable for use as cholinesterase acitivity inhibitors and relative preparation process | MEDIOLANUM FARMACEUTICI SRL (IT) | 1998-09-02 | — | — | EP | disclosed |
| US-5424451-A | Used as cholinesterase activity inhibitors | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1995-06-13 | — | — | US | disclosed |
| US-5302593-A | Aminoalkylcarbamic esters of eseroline suitable for use as chlorinesterase activity inhibitors | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1994-04-12 | — | — | US | disclosed |
| EP-0575954-A1 | Aminoalkylcarbamic esters of eseroline suitable for use as cholinesterase acitivity inhibitors and relative preparation process | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1993-12-29 | — | — | EP | disclosed |