Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.50 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.50 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551972 | 0.85 | NTRK1 (0.58) | NTRK1GAAKMT2AMEN1TSHR | |
| SCHEMBL8553463 | 0.84 | NTRK1 (0.65) | NTRK1GAAKMT2AMEN1TSHR | |
| SCHEMBL8554769 | 0.83 | NTRK1 (0.60) | NTRK1GAATSHRKCNJ6KCNJ5 | |
| SCHEMBL8553763 | 0.83 | NTRK1 (0.62) | NTRK1GAAKMT2AMEN1TSHR | |
| SCHEMBL8555682 | 0.83 | NTRK1 (0.62) | NTRK1GAATSHRKCNJ6KCNJ5 | |
| SCHEMBL8551416 | 0.82 | ALDH1A1 (0.70) | NTRK1GAATSHRKCNJ6KCNJ5 | |
| SCHEMBL8553577 | 0.82 | NTRK1 (0.61) | NTRK1GAAKMT2AMEN1TSHR | |
| SCHEMBL8555225 | 0.81 | NTRK1 (0.62) | NTRK1GAAKMT2AMEN1TSHR | |
| SCHEMBL8552018 | 0.81 | NTRK1 (0.62) | NTRK1GAATSHRKCNJ6KCNJ5 | |
| SCHEMBL8550596 | 0.80 | NTRK1 (0.65) | NTRK1GAAKMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |