Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | EGFR | P00533 | 6/20 | 0.44 |
| ▸ | AKT1 | P31749 | 6/20 | 0.44 |
| ▸ | AKT2 | P31751 | 6/20 | 0.44 |
| ▸ | AKT3 | Q9Y243 | 6/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557547 | 0.91 | TP53 (0.51) | TP53MAPTEGFRAKT1AKT2 | |
| SCHEMBL8554723 | 0.90 | TP53 (0.50) | TP53MAPTEGFRAKT1AKT2 | |
| SCHEMBL8556548 | 0.90 | THRB (0.53) | TP53MAPTEGFRAKT1AKT2 | |
| SCHEMBL8554499 | 0.90 | TP53 (0.57) | TP53MAPTEGFRAKT1AKT2 | |
| SCHEMBL8557170 | 0.88 | TP53 (0.46) | TP53MAPTEGFRAKT1AKT2 | |
| SCHEMBL8554193 | 0.87 | TP53 (0.46) | TP53MAPTEGFRAKT1AKT2 | |
| SCHEMBL8554779 | 0.86 | TP53 (0.37) | TP53MAPTEGFRAKT1AKT2 | |
| SCHEMBL8554698 | 0.83 | TP53 (0.46) | TP53MAPTEGFRAKT1AKT2 | |
| SCHEMBL8556217 | 0.80 | MAPK9 (0.41) | TP53MAPTEGFRAKT1AKT2 | |
| SCHEMBL8625711 | 0.79 | TP53 (0.43) | TP53MAPTEGFRAKT1AKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0554957-B1 | Thiazole derivatives of alkoxyacrylates with a fungicidal activity | MINI RICERCA SCIENT TECNOLOG (IT) | 1998-04-15 | — | — | EP | disclosed |
| US-5334609-A | Used in agriculture | MINISTERO DELL'UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECHNOLOGICA (IT) | 1994-08-02 | — | — | US | disclosed |
| EP-0554957-A2 | Thiazole derivatives of alkoxyacrylates with a fungicidal activity | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1993-08-11 | — | — | EP | disclosed |