Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557790 | 1.00 | NPSR1 (0.34) | NPSR1MAPTHPGDALDH1A1TSHR | |
| SCHEMBL8556516 | 1.00 | NPSR1 (0.34) | NPSR1MAPTHPGDALDH1A1TSHR | |
| SCHEMBL8558163 | 0.90 | MAPT (0.33) | NPSR1MAPTHPGDALDH1A1TSHR | |
| SCHEMBL8558157 | 0.90 | MAPT (0.33) | NPSR1MAPTHPGDALDH1A1TSHR | |
| SCHEMBL8558155 | 0.90 | MAPT (0.33) | NPSR1MAPTHPGDALDH1A1TSHR | |
| SCHEMBL8560721 | 0.89 | NPSR1 (0.33) | NPSR1 | |
| SCHEMBL8557095 | 0.81 | NPSR1 (0.35) | NPSR1MAPTHPGDALDH1A1TSHR | |
| SCHEMBL8557714 | 0.79 | HCRTR2 (0.37) | NPSR1MAPTHPGDBRD4CREBBP | |
| SCHEMBL8556603 | 0.79 | HCRTR2 (0.37) | NPSR1MAPTHPGDBRD4CREBBP | |
| SCHEMBL8556600 | 0.79 | HCRTR2 (0.37) | NPSR1MAPTHPGDBRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653426-B1 | Indole derivatives, salts thereof and heart affection therapeutic agent comprising the same | KOWA CO (JP) | 1998-07-22 | — | — | EP | disclosed |
| EP-0653426-A1 | Indole derivatives, salts thereof and heart affection therapeutic agent comprising the same | KOWA COMPANY, LTD. (JP) | 1995-05-17 | — | — | EP | disclosed |