Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MAP3K12 | Q12852 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1695102 | 0.74 | KDM4E (0.50) | HPGDALDH1A1KDM4EHSD17B10MAPK1 | |
| SCHEMBL18692985 | 0.74 | HPGD (0.42) | HPGDALDH1A1KDM4EHSD17B10FLT3 | |
| SCHEMBL24483396 | 0.72 | NPC1 (0.51) | HPGDALDH1A1KDM4EHSD17B10PKM | |
| SCHEMBL18693671 | 0.72 | NPC1 (0.47) | HPGDALDH1A1KDM4EHSD17B10PKM | |
| SCHEMBL1811782 | 0.72 | HPGD (0.44) | HPGDCTSKALDH1A1KDM4EHSD17B10 | |
| SCHEMBL31078454 | 0.72 | HPGD (0.40) | HPGDALDH1A1KDM4EHSD17B10PKM | |
| SCHEMBL1695151 | 0.72 | KDM4E (0.47) | HPGDALDH1A1KDM4EHSD17B10MAPK1 | |
| SCHEMBL18692782 | 0.71 | HPGD (0.43) | HPGDALDH1A1KDM4EHSD17B10HRH3 | |
| SCHEMBL18693143 | 0.71 | NPC1 (0.50) | HPGDALDH1A1KDM4EHSD17B10PKM | |
| SCHEMBL18694412 | 0.70 | MAPK13 (0.48) | HPGDALDH1A1KDM4EHSD17B10FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109575006-A | A kind of diazole pyrazole amide analog derivative and its microwave attenuation materials method and application | 中南民族大学 | 2019-04-05 | — | — | CN | disclosed |
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |