SCHEMBL8556841

SCHEMBL8556841

O=C(Nc1ccc(C(=O)N2Cc3ccccc3Cc3cc(Cl)ccc32)cc1)c1ccccc1Cl

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AVPR2 P30518 10/20 0.65
AVPR1A P37288 10/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8559571 0.94 AVPR2 (0.62) AVPR2AVPR1A
SCHEMBL8562554 0.94 AVPR2 (0.73) AVPR2AVPR1A
SCHEMBL8558993 0.91 AVPR2 (0.65) AVPR2AVPR1A
SCHEMBL8561962 0.90 AVPR2 (0.58) AVPR2AVPR1A
SCHEMBL8558900 0.90 AVPR2 (0.65) AVPR2AVPR1A
SCHEMBL8563344 0.89 AVPR2 (0.81) AVPR2AVPR1A
SCHEMBL8558027 0.89 AVPR2 (0.69) AVPR2AVPR1A
SCHEMBL8558428 0.88 AVPR2 (0.57) AVPR2AVPR1A
SCHEMBL8561595 0.88 ACHE (0.61) AVPR2AVPR1A
SCHEMBL8559508 0.87 AVPR2 (0.59) AVPR2AVPR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0640592-B1 N-acylated tricyclic azaheterorings useful as vasopressin antagonists AMERICAN CYANAMID CO (US) 1998-12-30 EP disclosed