Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.67 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrazine SCHEMBL8558416 | 0.98 | HRH3 (0.71) | HRH3KEAP1SMN1; SMN2MAPTSIGMAR1 | |
| SCHEMBL854695 | 0.97 | HRH3 (0.70) | HRH3KEAP1SMN1; SMN2MAPTSIGMAR1 | |
| SCHEMBL8554508 | 0.97 | HRH3 (0.70) | HRH3KEAP1SMN1; SMN2MAPTSIGMAR1 | |
| SCHEMBL6347703 | 0.97 | HRH3 (0.70) | HRH3KEAP1SMN1; SMN2MAPTSIGMAR1 | |
| SCHEMBL11179088 | 0.97 | HRH3 (0.70) | HRH3KEAP1SMN1; SMN2MAPTSIGMAR1 | |
| SCHEMBL7230416 | 0.95 | HRH3 (0.75) | HRH3KEAP1SMN1; SMN2MAPTSIGMAR1 | |
| SCHEMBL21799790 | 0.95 | HRH3 (0.75) | HRH3KEAP1SMN1; SMN2MAPTSIGMAR1 | |
| SCHEMBL21799504 | 0.95 | HRH3 (0.75) | HRH3KEAP1SMN1; SMN2MAPTSIGMAR1 | |
| SCHEMBL21799578 | 0.95 | HRH3 (0.75) | HRH3KEAP1SMN1; SMN2MAPTSIGMAR1 | |
| SCHEMBL491616 | 0.95 | HRH3 (0.75) | HRH3KEAP1SMN1; SMN2MAPTSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575954-B1 | Aminoalkylcarbamic esters of eseroline suitable for use as cholinesterase acitivity inhibitors and relative preparation process | MEDIOLANUM FARMACEUTICI SRL (IT) | 1998-09-02 | — | — | EP | disclosed |