Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.52 |
| ▸ | DRD4 | P21917 | 3/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558162 | 0.82 | ALOX5 (0.74) | ALOX5DRD4DRD2DRD3MEN1 | |
| SCHEMBL8552538 | 0.69 | ALOX5 (0.57) | ALOX5DRD4DRD2DRD3ALDH1A1 | |
| SCHEMBL8555043 | 0.69 | ALOX5 (0.80) | ALOX5DRD4DRD2DRD3MEN1 | |
| SCHEMBL8556159 | 0.69 | ALOX5 (0.80) | ALOX5DRD4DRD2DRD3MEN1 | |
| SCHEMBL8553220 | 0.69 | ALOX5 (1.00) | ALOX5DRD4DRD2DRD3MEN1 | |
| SCHEMBL8557565 | 0.68 | ALOX5 (0.77) | ALOX5DRD4DRD2DRD3ALDH1A1 | |
| SCHEMBL9304810 | 0.68 | ALOX5 (0.56) | ALOX5DRD4DRD2DRD3ALDH1A1 | |
| SCHEMBL9305207 | 0.68 | ALOX5 (0.56) | ALOX5DRD4DRD2DRD3ALDH1A1 | |
| SCHEMBL8554000 | 0.68 | ALOX5 (0.55) | ALOX5MEN1KMT2AALDH1A1PARP1 | |
| Hydrochloric Acid SCHEMBL8555007 | 0.67 | ALOX5 (0.75) | ALOX5DRD4DRD2DRD3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529452-B1 | 1,7-Condensed 3-(piperazinoalkyl)indol derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them | SOLVAY PHARM GMBH (DE) | 1998-11-11 | — | — | EP | disclosed |
| US-5324725-A | Antiinflammatory agent, antiallergen | KALI-CHEMIE PHARMA GMBH (DE) | 1994-06-28 | — | — | US | disclosed |
| CN-1069732-A | 1, the 2-that 7-a pair of horses going side by side is closed (piperazine alkyl) indole derivatives and preparation method and intermediate product and the medicament that contains these compounds | KALI CHEMIE PHARMA GMBH (DE) | 1993-03-10 | — | — | CN | disclosed |
| EP-0529452-A2 | 1,7-Condensed 2-(piperazinoalkyl)indol derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them | Kali-Chemie Pharma GmbH (DE) | 1993-03-03 | — | — | EP | disclosed |