Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 19/20 | 0.84 |
| ▸ | EBP | Q15125 | 1/20 | 0.84 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.69 |
| ▸ | DRD2 | P14416 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.69 |
| ▸ | HTR2A | P28223 | 1/20 | 0.69 |
| ▸ | HTR2C | P28335 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | HTR2B | P41595 | 1/20 | 0.69 |
| ▸ | MTOR | P42345 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | BLM | P54132 | 1/20 | 0.68 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9375143 | 0.92 | SIGMAR1 (1.00) | SIGMAR1EBPTP53CYP1A2CYP3A4 | |
| SCHEMBL9374660 | 0.91 | SIGMAR1 (1.00) | SIGMAR1EBPTP53CYP1A2CYP3A4 | |
| SCHEMBL7435097 | 0.91 | SIGMAR1 (0.83) | SIGMAR1EBPTP53CYP1A2CYP3A4 | |
| SCHEMBL8013750 | 0.90 | SIGMAR1 (0.83) | SIGMAR1EBPTP53CYP1A2CYP3A4 | |
| SCHEMBL7373780 | 0.87 | SIGMAR1 (1.00) | SIGMAR1EBPTP53CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL7383946 | 0.86 | SIGMAR1 (1.00) | SIGMAR1EBPMEN1BLMPMP22 | |
| SCHEMBL9374544 | 0.85 | SIGMAR1 (1.00) | SIGMAR1EBPTP53CYP1A2CYP3A4 | |
| SCHEMBL2758088 | 0.84 | SIGMAR1 (0.70) | SIGMAR1EBPTP53CYP1A2CYP3A4 | |
| SCHEMBL2758036 | 0.84 | SIGMAR1 (0.70) | SIGMAR1EBPTP53CYP1A2CYP3A4 | |
| SCHEMBL240450 | 0.83 | SIGMAR1 (0.68) | SIGMAR1EBPTP53CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649407-B1 | DIMERIC PIPERIDINE, TETRAHYDROPYRIDINE AND PIPERAZINE DERIVATIVES | LUNDBECK & CO AS H (DK) | 1998-08-05 | — | — | EP | claimed |