SCHEMBL8557522

SCHEMBL8557522

CCCCCCCC(=O)OCCC(C)(C)C

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.71
DNM1 Q05193 1/20 0.59
PAM P19021 2/20 0.55
TSHR P16473 1/20 0.51
MAPT P10636 1/20 0.51
PRSS1 P07477 1/20 0.51
PRSS2 P07478 1/20 0.51
PRSS3 P35030 1/20 0.51
LMNA P02545 4/20 0.50
NAAA Q02083 1/20 0.50
ALDH1A1 P00352 1/20 0.50
KDM4E B2RXH2 1/20 0.49
DUSP3 P51452 1/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
HTR2C P28335 1/20 0.49
PRKCA P17252 1/20 0.46
PRKCE Q02156 1/20 0.46
PRKCQ Q04759 1/20 0.46
PRKCD Q05655 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11079332 1.00 DGKA (0.71) DGKADNM1PAMTSHRMAPT
SCHEMBL756972 0.98 DGKA (0.68) DGKADNM1PAMTSHRMAPT
SCHEMBL9446486 0.93 DGKA (0.60) DGKADNM1PAMTSHRMAPT
SCHEMBL8334997 0.92 DGKA (0.59) DGKADNM1PAMTSHRMAPT
SCHEMBL14081984 0.91 DGKA (0.69) DGKADNM1PAMTSHRMAPT
SCHEMBL18195577 0.91 DGKA (0.59) DGKADNM1PAMTSHRMAPT
SCHEMBL3309964 0.91 DGKA (0.59) DGKAMAPTLMNAALDH1A1DUSP3
SCHEMBL18177234 0.89 DGKA (0.67) DGKADNM1PAMTSHRMAPT
SCHEMBL18177237 0.89 DGKA (0.67) DGKADNM1PAMTSHRMAPT
SCHEMBL15147921 0.89 DGKA (0.67) DGKADNM1PAMTSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5354487-A Fluorinated, crosslinked butadiene polymer NIPPON OIL CO., LTD. (JP) 1994-10-11 US claimed
EP-0450983-A2 Compositions with high lubrication performance and light coloration NIPPON OIL CO. LTD. (JP) 1991-10-09 EP claimed
EP-4407015-A1 GREASE COMPOSITION AND GREASE-SEALED BEARING NTN Corporation (JP) 2024-07-31 EP disclosed
US-20160317458-A1 Lipids and Lipid Compositions for the Delivery of Active Agents NOVARTIS AG (CH) 2016-11-03 US disclosed
US-5739088-A ALKALINE EARTH METAL BORATE NIPPON OIL CO., LTD. (JP) 1998-04-14 US disclosed
US-5354487-A Fluorinated, crosslinked butadiene polymer NIPPON OIL CO., LTD. (JP) 1994-10-11 US disclosed
EP-0450983-A2 Compositions with high lubrication performance and light coloration NIPPON OIL CO. LTD. (JP) 1991-10-09 EP disclosed
US-4759861-A Consists of an aliphatic mono- or di-carboxylic acid, a dimer or trimer of said dicarboxylic acid, petroleum sulfonic acid and naphthenic acid or salt NIPPON OIL CO., LTD. (JP) 1988-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160317458-A1 Lipids and Lipid Compositions for the Delivery of Active Agents SGMS1, PHOSPHO1, LIPA DGKA 1600/4885DNM1 645/4885PAM 4116/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.