Acetic Acid Propyl Ester

Acetic Acid Propyl Ester

SCHEMBL8557617

CCCOC(C)=O.N#CS

nearest known ligand 0.54

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.54
TSHR P16473 3/20 0.46
LMNA P02545 2/20 0.44
HSD17B10 Q99714 1/20 0.44
CHRM1 P11229 3/20 0.41
CHRM5 P08912 2/20 0.41
CHRM3 P20309 2/20 0.41
PGR P06401 1/20 0.41
CHRM2 P08172 1/20 0.41
CHRM4 P08173 1/20 0.41
HTR1A P08908 1/20 0.41
CHRNB2 P17787 1/20 0.41
TBXA2R P21731 1/20 0.41
CHRNB4 P30926 1/20 0.41
CHRNA3 P32297 1/20 0.41
CHRNA7 P36544 1/20 0.41
CHRNA4 P43681 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CHRNA10 Q9GZZ6 1/20 0.41
CHRNA9 Q9UGM1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid Propyl Ester SCHEMBL4537569 0.88 ALDH1A1 (0.56) ALDH1A1TSHRLMNAHSD17B10CHRM1
Acetic Acid Propyl Ester SCHEMBL18229929 0.88
Acetic Acid Propyl Ester SCHEMBL28142007 0.86 ALDH1A1 (0.54) ALDH1A1TSHRLMNAHSD17B10CHRM1
Acetic Acid Propyl Ester SCHEMBL23495512 0.85 ALDH1A1 (0.70) ALDH1A1TSHRLMNAHSD17B10CHRM1
Acetic Acid Propyl Ester SCHEMBL14991 0.85
Acetic Acid Propyl Ester SCHEMBL27827816 0.83 ALDH1A1 (0.61) ALDH1A1TSHRLMNAHSD17B10CHRM1
Acetic Acid Propyl Ester SCHEMBL28836589 0.83 ALDH1A1 (0.61) ALDH1A1TSHRLMNAHSD17B10CHRM1
Acetic Acid Propyl Ester SCHEMBL11404549 0.83
Acetic Acid Propyl Ester SCHEMBL9807768 0.83
Acetic Acid Propyl Ester SCHEMBL21749216 0.83 ALDH1A1 (0.67) ALDH1A1TSHRLMNAHSD17B10CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0562440-B1 Imidazopyridazines as antiasthmatics TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1998-12-23 EP disclosed
US-5491145-A ANTIASTHMA, ANTI-PLATELET ACTIVATING FACTOR BRONCHOCONSTRICTION-INHIBITING AGENTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1996-02-13 US disclosed
EP-0562440-A1 Imidazopyridazines as antiasthmatics TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-09-29 EP disclosed