Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 6/20 | 0.46 |
| ▸ | RXRB | P28702 | 4/20 | 0.46 |
| ▸ | RARB | P10826 | 8/20 | 0.45 |
| ▸ | RARG | P13631 | 8/20 | 0.45 |
| ▸ | RARA | P10276 | 5/20 | 0.45 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.43 |
| ▸ | CYP26A1 | O43174 | 4/20 | 0.43 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.43 |
| ▸ | HNF4A | P41235 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555653 | 0.91 | RXRA (0.47) | RXRARXRBRARBRARGRARA | |
| SCHEMBL8556008 | 0.85 | RXRA (0.48) | RXRARXRBRARBRARGRARA | |
| SCHEMBL8839167 | 0.85 | RXRA (0.51) | RXRARXRBRARBRARGRARA | |
| SCHEMBL8555833 | 0.83 | RXRA (0.46) | RXRARXRBRARBRARGRARA | |
| SCHEMBL8108587 | 0.80 | RXRA (0.53) | RXRARXRBRARBRARGRARA | |
| SCHEMBL8555469 | 0.80 | RXRA (0.49) | RXRARXRBRARBRARGRARA | |
| Hydrochloric Acid SCHEMBL8092985 | 0.79 | RXRA (0.52) | RXRARXRBRARBRARGRARA | |
| SCHEMBL8557720 | 0.77 | RARB (0.48) | RXRARXRBRARBRARGRARA | |
| SCHEMBL8100902 | 0.77 | RARB (0.60) | RXRARXRBRARBRARGRARA | |
| SCHEMBL8092981 | 0.76 | RXRA (0.52) | RXRARXRBRARBRARGRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5709867-A | TREATMENT OF DERMATOLOGICAL, RHEUMATIC, RESPIRATORY, CARDIOVASCULAR, AND OPHTHALMOLOGICAL DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-01-20 | — | — | US | claimed |
| US-5709867-A | TREATMENT OF DERMATOLOGICAL, RHEUMATIC, RESPIRATORY, CARDIOVASCULAR, AND OPHTHALMOLOGICAL DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-01-20 | — | — | US | disclosed |