Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 16/20 | 0.47 |
| ▸ | RXRB | P28702 | 14/20 | 0.47 |
| ▸ | RXRG | P48443 | 14/20 | 0.47 |
| ▸ | RARB | P10826 | 2/20 | 0.39 |
| ▸ | RARG | P13631 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.38 |
| ▸ | HNF4A | P41235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555475 | 0.90 | RXRA (0.49) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8555660 | 0.88 | RXRA (0.47) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8556010 | 0.86 | RXRA (0.49) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8555837 | 0.84 | RXRA (0.46) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8100910 | 0.82 | RXRA (0.60) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8556722 | 0.79 | RXRA (0.43) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8559129 | 0.77 | RXRA (0.45) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8353210 | 0.76 | RXRA (0.45) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8555716 | 0.75 | RXRA (0.44) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8352261 | 0.74 | PTPN1 (0.39) | RXRARXRBRXRGPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5709867-A | TREATMENT OF DERMATOLOGICAL, RHEUMATIC, RESPIRATORY, CARDIOVASCULAR, AND OPHTHALMOLOGICAL DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-01-20 | — | — | US | claimed |
| US-5709867-A | TREATMENT OF DERMATOLOGICAL, RHEUMATIC, RESPIRATORY, CARDIOVASCULAR, AND OPHTHALMOLOGICAL DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-01-20 | — | — | US | disclosed |