Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 18/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 18/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27462928 | 0.90 | ITGB3 (0.47) | ITGB3ITGA2BALOX15F10 | |
| SCHEMBL7419652 | 0.85 | ITGB3 (0.53) | ITGB3ITGA2B | |
| SCHEMBL9029210 | 0.83 | ITGB3 (0.53) | ITGB3ITGA2B | |
| SCHEMBL7416061 | 0.83 | ITGB3 (0.56) | ITGB3ITGA2B | |
| SCHEMBL9028484 | 0.83 | ITGB3 (0.47) | ITGB3ITGA2BF10 | |
| SCHEMBL9028236 | 0.82 | ITGB3 (0.44) | ITGB3ITGA2B | |
| SCHEMBL9028226 | 0.82 | ITGB3 (0.44) | ITGB3ITGA2B | |
| SCHEMBL8427476 | 0.82 | HTT (0.47) | — | |
| SCHEMBL9029205 | 0.81 | ITGB3 (0.46) | ITGB3ITGA2BF10 | |
| SCHEMBL7419733 | 0.81 | ITGB3 (0.54) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825994-A1 | AMIDINE DERIVATIVES USEFUL AS ANTI-PLATELET AGGREGATION INHIBITORS AND VASODILATORS | G.D. SEARLE & CO. (US) | 1998-03-04 | — | — | EP | disclosed |
| US-5674894-A | Amidine derivatives useful as platelet aggregation inhibitors and vasodilators | G.D. SEARLE & CO. (US) | 1997-10-07 | — | — | US | disclosed |
| WO-1996036639-A1 | AMIDINE DERIVATIVES USEFUL AS ANTI-PLATELET AGGREGATION INHIBITORS AND VASODILATORS | G.D. SEARLE & CO. (US) | 1996-11-21 | — | — | WO | disclosed |