Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 17/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7550799 | 0.86 | CCKBR (0.78) | CCKBRKCNH2MAPT | |
| SCHEMBL7550802 | 0.86 | CCKBR (0.78) | CCKBRKCNH2MAPT | |
| SCHEMBL7546371 | 0.78 | CCKBR (0.65) | CCKBRKCNH2 | |
| SCHEMBL641958 | 0.76 | CCKBR (1.00) | CCKBRKCNH2CYP3A4MAPTTSHR | |
| SCHEMBL7547182 | 0.76 | CCKBR (0.72) | CCKBRKCNH2MAPT | |
| SCHEMBL7547190 | 0.76 | CCKBR (0.72) | CCKBRKCNH2MAPT | |
| SCHEMBL7552167 | 0.76 | CCKBR (0.75) | CCKBRKCNH2MAPT | |
| SCHEMBL7552157 | 0.76 | CCKBR (0.75) | CCKBRKCNH2MAPT | |
| SCHEMBL9866481 | 0.76 | CCKBR (0.64) | CCKBRKCNH2 | |
| SCHEMBL7545616 | 0.75 | CYP3A4 (0.60) | CCKBRCYP3A4MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934282-A1 | 1,4-BENZODIAZEPINONES AND THEIR USES AS CCK ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998015535-A1 | 1,4-BENZODIAZEPINONES AND THEIR USES AS CCK ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-04-16 | — | — | WO | disclosed |