SCHEMBL8558119

SCHEMBL8558119

CC1OC1c1cccc(OP(=O)(O)O)c1C1OC1C

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
INPPL1 O15357 9/20 0.47
INPP5A Q14642 5/20 0.47
INPP5B P32019 2/20 0.47
SRC P12931 5/20 0.39
KDM4E B2RXH2 1/20 0.39
USP2 O75604 1/20 0.39
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.39
PDE3A Q14432 1/20 0.39
HSD17B10 Q99714 1/20 0.39
AKT1 P31749 1/20 0.38
HTR2A P28223 3/20 0.33
HTR2C P28335 2/20 0.33
HTR2B P41595 2/20 0.33
HTR1A P08908 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8558116 0.87 MAPT (0.31) INPPL1INPP5AINPP5B
SCHEMBL8555065 0.75 SMN1; SMN2 (0.30) KDM4E
SCHEMBL5951744 0.67 INPPL1 (0.45) INPPL1INPP5AINPP5BSRCKDM4E
SCHEMBL2573126 0.67 INPPL1 (0.70) INPPL1INPP5AINPP5BSRCKDM4E
SCHEMBL6474455 0.66 INPPL1 (0.41) INPPL1INPP5AINPP5BSRCKDM4E
SCHEMBL6860646 0.66 INPPL1 (0.44) INPPL1INPP5AINPP5BSRCKDM4E
SCHEMBL5952374 0.66 INPPL1 (0.44) INPPL1INPP5AINPP5BSRCKDM4E
SCHEMBL8386747 0.66 INPPL1 (0.68) INPPL1INPP5AINPP5BSRCKDM4E
SCHEMBL5606360 0.66 INPPL1 (1.00) INPPL1INPP5AINPP5BSRCKDM4E
SCHEMBL759513 0.64 MAPT (0.67) INPPL1INPP5AINPP5BSRCKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5728468-A EPOXY RESIN NETWORKS AND ALLYL GROUP MONOMERS AKZO NOBEL N.V. (NL) 1998-03-17 US claimed
EP-0614470-B1 PHOSPOROUS CONTAINING RESIN AKZO NOBEL NV (NL) 1996-06-12 EP claimed