SCHEMBL6474455

SCHEMBL6474455

CC1(C)CC(c2cccc(OP(=O)(O)O)c2C2CC(C)(C)NC(C)(C)C2)CC(C)(C)N1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
INPPL1 O15357 1/20 0.41
INPP5B P32019 1/20 0.41
INPP5A Q14642 1/20 0.41
SRC P12931 2/20 0.36
GAA P10253 1/20 0.35
EZH2 Q15910 6/20 0.35
USP2 O75604 2/20 0.34
HSD17B10 Q99714 2/20 0.34
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
PDE3A Q14432 1/20 0.34
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6474451 0.89 GAA (0.34) GAAEZH2USP2HSD17B10KMT2A
SCHEMBL11176319 0.83 INPPL1 (0.40) INPPL1INPP5BINPP5ASRCUSP2
SCHEMBL2343615 0.78 GAA (0.34) GAAEZH2USP2HSD17B10ALDH1A1
SCHEMBL2343611 0.78 KDM1A (0.33) GAAEZH2USP2HSD17B10ALDH1A1
SCHEMBL8769447 0.78 KDM1A (0.40) GAAEZH2KDM4EALDH1A1KMT2A
SCHEMBL25282055 0.71 KMT2A (0.41) GAAKMT2AMEN1L3MBTL1
SCHEMBL15910478 0.69 KMT2A (0.43) GAAEZH2HSD17B10KMT2AMEN1
Formamide SCHEMBL28040635 0.68 KMT2A (0.38) GAAKMT2AMEN1L3MBTL1
SCHEMBL8558119 0.66 INPPL1 (0.47) INPPL1INPP5BINPP5ASRCUSP2
SCHEMBL4012295 0.66 ALOX15 (0.41) GAAEZH2HSD17B10KDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150030832-A1 TRANSPARENT LAYERED STRUCTURE AND METHOD FOR PRODUCING THE SAME MAZDA MOTOR CORPORATION (JP) 2015-01-29 US disclosed
US-6846567-B1 Surface-protected transparent plastic composite TEIJIN CHEMICALS, LTD. (JP) 2005-01-25 US disclosed