Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 7/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19344687 | 0.97 | MEN1 (0.50) | MEN1KMT2AMAOBMAOAALOX5 | |
| SCHEMBL1333722 | 0.87 | MAOB (0.56) | MAOBMAOAALOX5BCHECYP4F2 | |
| SCHEMBL241348 | 0.85 | LMNA (0.55) | MEN1KMT2AMAOBMAOABCHE | |
| SCHEMBL11387676 | 0.81 | CYP3A4 (0.53) | MEN1KMT2AMAOBMAOABCHE | |
| SCHEMBL14660991 | 0.81 | MAOB (0.49) | MAOBMAOABCHECYP4F2CYP4A11 | |
| SCHEMBL4674930 | 0.80 | MEN1 (0.70) | MEN1KMT2AMAOBMAOAALOX5 | |
| SCHEMBL10735742 | 0.80 | MEN1 (0.46) | MEN1KMT2AMAOBMAOAALOX5 | |
| SCHEMBL28185132 | 0.77 | MEN1 (0.59) | MEN1KMT2AMAOBMAOAALOX5 | |
| SCHEMBL5172920 | 0.75 | CYP3A4 (0.59) | MAOBBCHECYP1A2PPARG | |
| SCHEMBL15902884 | 0.75 | MRGPRX4 (0.46) | MEN1KMT2AMAOBMAOAALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5795907-A | Gastin and CCK receptor ligands | JAMES BLACK FOUNDATION LIMITED (GB) | 1998-08-18 | — | — | US | disclosed |