Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8603712 | 0.86 | NR1I2 (0.37) | NR1I2CYP3A4CYP2D6NPC1NFKB1 | |
| SCHEMBL8555193 | 0.82 | NR1I2 (0.41) | NR1I2CYP3A4CYP2D6PPARANPC1 | |
| SCHEMBL9089893 | 0.81 | NR1I2 (0.59) | NR1I2CYP3A4CYP2D6PPARANPC1 | |
| SCHEMBL8553984 | 0.81 | NR1I2 (0.34) | NR1I2CYP3A4CYP2D6NPC1NFKB1 | |
| SCHEMBL8557958 | 0.79 | NR1I2 (0.39) | NR1I2CYP3A4CYP2D6NPC1NFKB1 | |
| SCHEMBL8553973 | 0.78 | NR1I2 (0.41) | NR1I2CYP3A4CYP2D6NPC1NFKB1 | |
| SCHEMBL14191677 | 0.78 | NR1I2 (0.45) | NR1I2CYP3A4CYP2D6PPARA | |
| SCHEMBL8553780 | 0.77 | NPC1 (0.36) | NR1I2CYP3A4CYP2D6NPC1NFKB1 | |
| SCHEMBL10504981 | 0.77 | NR1I2 (0.54) | NR1I2CYP3A4CYP2D6NPC1NFKB1 | |
| SCHEMBL9275630 | 0.77 | NR1I2 (0.32) | NR1I2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846986-A | Therapeutic phenoxyalkylazoles and phenoxyalkylazines | SANOFI (FR) | 1998-12-08 | — | — | US | disclosed |
| US-5721261-A | TREATING PICORNAVIRUS INFECTIONS | SANOFI PHARMACEUTICALS, INC. (US) | 1998-02-24 | — | — | US | disclosed |
| US-5552420-A | TREATING PICORNAVIRAL INFECTIONS | STERLING WINTHROP INC. (US) | 1996-09-03 | — | — | US | disclosed |