Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8866731 | 0.79 | CCKBR (0.51) | CCKBREPHX2 | |
| SCHEMBL8866156 | 0.78 | CCKBR (0.53) | CCKBREPHX2 | |
| SCHEMBL8621950 | 0.77 | CCKBR (0.61) | CCKBREPHX2 | |
| SCHEMBL8561053 | 0.75 | CCKBR (0.79) | CCKBR | |
| SCHEMBL8557455 | 0.75 | CCKBR (0.47) | CCKBREPHX2 | |
| SCHEMBL8866621 | 0.75 | CCKBR (0.64) | CCKBREPHX2 | |
| SCHEMBL8865990 | 0.74 | CCKBR (0.63) | CCKBREPHX2 | |
| SCHEMBL8564644 | 0.73 | CCKBR (0.49) | CCKBREPHX2 | |
| SCHEMBL14072264 | 0.73 | EPHX2 (0.56) | CCKBREPHX2 | |
| SCHEMBL8557103 | 0.72 | CCKBR (0.44) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710230-B1 | 1,5-BENZODIAZEPINE DERIVATIVES USEFUL AS CCK OR GASTRIN ANTAGONISTS | GLAXO WELLCOME SPA (IT) | 1998-09-16 | — | — | EP | disclosed |
| US-5716953-A | MODIFIERS OF GASTRIN AND CHOLECYSTOKININS | GLAXO WELLCOME S.P.A. (IT) | 1998-02-10 | — | — | US | disclosed |