Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8750392 | 0.83 | ACHE (0.48) | ACP3AOC3EPHX1ACHEALDH1A1 | |
| SCHEMBL28495047 | 0.83 | HCAR2 (0.39) | TAAR1ALDH1A1OPRK1SLC6A3 | |
| SCHEMBL9065878 | 0.75 | ACHE (0.48) | ACP3AOC3EPHX1ACHEALDH1A1 | |
| SCHEMBL7518652 | 0.74 | ACP3 (0.50) | ACP3AOC3EPHX1ACHETAAR1 | |
| SCHEMBL19122369 | 0.74 | AOC3 (0.54) | ACP3AOC3EPHX1ACHEALDH1A1 | |
| SCHEMBL9070317 | 0.74 | AOC3 (0.54) | ACP3AOC3EPHX1ACHEALDH1A1 | |
| SCHEMBL19817007 | 0.73 | TP53 (0.38) | ACP3AOC3EPHX1ACHEALDH1A1 | |
| SCHEMBL1812638 | 0.73 | ACHE (0.50) | ACP3AOC3EPHX1ACHEALDH1A1 | |
| SCHEMBL30647112 | 0.73 | ACHE (0.50) | ACP3AOC3EPHX1ACHEALDH1A1 | |
| SCHEMBL30647223 | 0.73 | ACHE (0.50) | ACP3AOC3EPHX1ACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846986-A | Therapeutic phenoxyalkylazoles and phenoxyalkylazines | SANOFI (FR) | 1998-12-08 | — | — | US | disclosed |
| US-5721261-A | TREATING PICORNAVIRUS INFECTIONS | SANOFI PHARMACEUTICALS, INC. (US) | 1998-02-24 | — | — | US | disclosed |
| US-5552420-A | TREATING PICORNAVIRAL INFECTIONS | STERLING WINTHROP INC. (US) | 1996-09-03 | — | — | US | disclosed |