Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19612213 | 0.92 | KDM4E (0.49) | NQO1KDM4EAKR1C3AKR1C2CA12 | |
| SCHEMBL19612312 | 0.92 | KDM4E (0.49) | NQO1KDM4EAKR1C3AKR1C2CA12 | |
| SCHEMBL23458226 | 0.89 | NQO1 (0.62) | NQO1KDM4EAKR1C3AKR1C2CA12 | |
| SCHEMBL29779700 | 0.89 | NQO1 (0.62) | NQO1KDM4EAKR1C3AKR1C2CA12 | |
| SCHEMBL3821099 | 0.89 | NQO1 (0.62) | NQO1KDM4EAKR1C3AKR1C2CA12 | |
| SCHEMBL3825385 | 0.89 | NQO1 (0.68) | NQO1KDM4EAKR1C3AKR1C2CA12 | |
| SCHEMBL29629327 | 0.89 | NQO1 (0.68) | NQO1KDM4EAKR1C3AKR1C2CA12 | |
| SCHEMBL17912862 | 0.88 | NQO1 (0.46) | NQO1KDM4EAKR1C3AKR1C2CA12 | |
| SCHEMBL17912833 | 0.88 | NQO1 (0.46) | NQO1KDM4EAKR1C3AKR1C2CA12 | |
| SCHEMBL17912805 | 0.87 | NQO1 (0.45) | NQO1KDM4EAKR1C3AKR1C2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756730-A | Process for preparing analgesic compounds | SANKYO COMPANY, LIMITED (JP) | 1998-05-26 | — | — | US | disclosed |
| CN-1036004-C | Process for preparing analgesic carboxylic acid amide derivatives | SANKYO CO (JP) | 1997-10-01 | — | — | CN | disclosed |
| US-5656758-A | AMIDATION OF AN AMINE-CONTAINING THIOMORPHOLINE OR PIPERAZINE COMPOUND | SANKYO COMPANY, LIMITED (JP) | 1997-08-12 | — | — | US | disclosed |
| CN-1034731-C | Process for preparing analgesic carboxylic acid amide derivatives | SANKYO CO (JP) | 1997-04-30 | — | — | CN | disclosed |
| US-5512567-A | KAPPA-RECEPTOR AGONISTS | SANKYO COMPANY, LIMITED (JP) | 1996-04-30 | — | — | US | disclosed |
| CN-1030450-C | Preparation of analgesic carboxylic acid amides derivative | SANKYO CO (JP) | 1995-12-06 | — | — | CN | disclosed |
| CN-1079741-A | The preparation method of analgesic carboxylic acid amide derivatives | SANKYO CO (JP) | 1993-12-22 | — | — | CN | disclosed |
| CN-1079740-A | The preparation method of analgesic carboxylic acid amide derivatives | SANKYO CO (JP) | 1993-12-22 | — | — | CN | disclosed |
| US-5270327-A | Piperidine derivatives | SANKYO COMPANY, LIMITED (JP) | 1993-12-14 | — | — | US | disclosed |
| CN-1078461-A | The preparation method of analgesic carboxylic acid amide derivatives | SANKYO CO (JP) | 1993-11-17 | — | — | CN | disclosed |
| CN-1022185-C | Process for preparing analgesic carboxylic acid amide derivatives | SANKYO CO (JP) | 1993-09-22 | — | — | CN | disclosed |
| EP-0356247-B1 | ANALGESIC CARBOXYLIC ACID AMIDE DERIVATIVES | Sankyo Company Limited (JP) | 1993-03-17 | — | — | EP | disclosed |
| US-5021413-A | Analgesic thiomorpholins their preparation, and pharmaceutical compositions containing them | SANKYO COMPANY LIMITED (JP) | 1991-06-04 | — | — | US | disclosed |
| CN-1040791-A | ANALGESIC CARBOXYLIC ACID AMIDE DERIVATIVES | SANKYO CO (JP) | 1990-03-28 | — | — | CN | disclosed |
| EP-0356247-A1 | Analgesic carboxylic acid amide derivatives | Sankyo Company Limited (JP) | 1990-02-28 | — | — | EP | disclosed |
| US-4229274-A | PHOTOINITIATOR, PHOTOSENSITIZER, QUENCHER, AND COMPOUNDS CONTAINING ACRYLYLOXY GROUPS | PPG INDUSTRIES, INC. (US) | 1980-10-21 | — | — | US | disclosed |