Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | LMNA | P02545 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.49 |
| ▸ | CCR6 | P51684 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4594864 | 0.83 | NCEH1 (0.64) | NCEH1TSHRCYP3A4ALDH1A1MAPT | |
| SCHEMBL29625716 | 0.83 | NCEH1 (0.64) | NCEH1TSHRCYP3A4ALDH1A1MAPT | |
| SCHEMBL24150726 | 0.81 | POLB (0.42) | NCEH1TSHRALDH1A1LMNAMAPT | |
| SCHEMBL10614565 | 0.79 | MAPT (0.50) | TSHRCYP3A4ALDH1A1LMNAMAPT | |
| SCHEMBL17207333 | 0.78 | NCEH1 (0.58) | NCEH1TSHRCYP3A4ALDH1A1LMNA | |
| SCHEMBL18989532 | 0.78 | ALDH1A1 (0.53) | TSHRALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL11623131 | 0.77 | NCEH1 (0.72) | NCEH1TSHRCYP3A4ALDH1A1LMNA | |
| SCHEMBL8623033 | 0.77 | NCEH1 (0.57) | NCEH1TSHRCYP3A4ALDH1A1LMNA | |
| SCHEMBL12363753 | 0.77 | TSHR (0.64) | NCEH1TSHRCYP3A4ALDH1A1LMNA | |
| SCHEMBL14118397 | 0.76 | NCEH1 (0.45) | NCEH1TSHRCYP3A4ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057588-B | Synthesis method of 8-amino-2-naphthol | 大连双硼医药化工有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-114057588-A | Synthesis method of 8-amino-2-naphthol | 大连双硼医药化工有限公司 | 2022-02-18 | — | — | CN | disclosed |
| EP-0543307-B1 | Nootropic agent | SANWA KAGAKU KENKYUSHO CO (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5434165-A | Nootropic agents, compositions of, and method of use thereof | SANAWA KAGAKU KENKYUSHO COMPANY, LTD. (JP) | 1995-07-18 | — | — | US | disclosed |
| US-4284704-A | Photographic elements with incorporated hydrogen source photoreductant and tetrazolium salt | EASTMAN KODAK COMPANY (US) | 1981-08-18 | — | — | US | disclosed |