Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 6/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558840 | 0.83 | NOX1 (0.43) | ALOX15HSD17B10GAANPSR1MAPT | |
| SCHEMBL8561569 | 0.81 | MEN1 (0.47) | ALOX15HSD17B10GAANPSR1MAPT | |
| SCHEMBL4510651 | 0.77 | GAA (0.52) | ALOX15HSD17B10GAANPSR1MAPT | |
| SCHEMBL7069691 | 0.74 | NOX1 (0.59) | ALOX15GAANPSR1MAPTMEN1 | |
| SCHEMBL8817021 | 0.74 | MEN1 (0.45) | NPSR1MAPTMEN1KMT2AALOX12 | |
| SCHEMBL8558177 | 0.71 | NOX1 (0.58) | ALOX15HSD17B10GAANPSR1MAPT | |
| SCHEMBL25002667 | 0.69 | MEN1 (0.48) | NPSR1MAPTMEN1KMT2AALOX12 | |
| SCHEMBL8559836 | 0.69 | MEN1 (0.36) | GAANPSR1MAPTMEN1KMT2A | |
| SCHEMBL8556950 | 0.69 | NOX1 (0.41) | GAAMAPTMEN1KMT2ABCHE | |
| SCHEMBL8562468 | 0.68 | NOX1 (0.58) | ALOX15HSD17B10GAANPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |
| EP-0640592-A1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID COMPANY (US) | 1995-03-01 | — | — | EP | disclosed |