Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 3/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559836 | 0.89 | MEN1 (0.36) | NOX1BCHEACHEMEN1KMT2A | |
| SCHEMBL8558840 | 0.86 | NOX1 (0.43) | NOX1BCHEACHEMEN1KMT2A | |
| SCHEMBL8561569 | 0.81 | MEN1 (0.47) | NOX1BCHEACHEMEN1KMT2A | |
| SCHEMBL8562468 | 0.78 | NOX1 (0.58) | NOX1BCHEACHEMEN1KMT2A | |
| SCHEMBL8558177 | 0.69 | NOX1 (0.58) | NOX1BCHEACHEMEN1KMT2A | |
| SCHEMBL8559064 | 0.69 | ALOX15 (0.41) | NOX1BCHEACHEMEN1KMT2A | |
| SCHEMBL8562293 | 0.67 | GAA (0.40) | MEN1KMT2AGAAMAPTNPC1 | |
| SCHEMBL30935803 | 0.64 | BRPF1 (0.44) | MEN1KMT2AGAAMAPTL3MBTL1 | |
| SCHEMBL7858934 | 0.63 | ALOX15 (0.63) | NOX1BCHEACHEGAAGSK3B | |
| SCHEMBL13113542 | 0.62 | MEN1 (0.66) | ACHEMEN1KMT2AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |
| EP-0640592-A1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID COMPANY (US) | 1995-03-01 | — | — | EP | disclosed |