Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1632128 | 0.87 | S1PR4 (0.46) | PTGDR2LMNAHTTUSP2ALPL | |
| SCHEMBL16244453 | 0.86 | PTGDR2 (0.60) | PTGDR2LMNAMAPK1HTTUSP2 | |
| SCHEMBL17847407 | 0.83 | PTGDR2 (0.57) | PTGDR2LMNAMAPK1HTTUSP2 | |
| SCHEMBL9980395 | 0.82 | LMNA (0.40) | LMNAMAPK1HTTALOX15KDM4E | |
| SCHEMBL17847400 | 0.82 | LMNA (0.43) | PTGDR2LMNAMAPK1HTTUSP2 | |
| SCHEMBL13642025 | 0.80 | KDM4E (0.50) | LMNAHTTKDM4EHPGDALDH1A1 | |
| SCHEMBL19639467 | 0.79 | LMNA (0.40) | PTGDR2LMNAMAPK1HTTUSP2 | |
| SCHEMBL28367568 | 0.79 | HPGD (0.36) | LMNAKDM4EHPGDALDH1A1KMT2A | |
| SCHEMBL2046907 | 0.78 | HTT (0.49) | LMNAMAPK1HTTALOX15KDM4E | |
| SCHEMBL16008334 | 0.78 | LMNA (0.47) | LMNAMAPK1HTTALOX15KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0679628-B1 | Polyene derivatives, pharmaceutical and cosmetic composition containing them and their use | CIRD GALDERMA (FR) | 1998-04-22 | — | — | EP | disclosed |
| EP-0679628-A1 | Polyene derivatives, pharmaceutical and cosmetic composition containing them and their use | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1995-11-02 | — | — | EP | disclosed |