Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 5/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559281 | 1.00 | NCEH1 (0.47) | NCEH1RXFP1KMT2ALMNAPTPN1 | |
| SCHEMBL8557407 | 0.82 | PPARG (0.47) | NCEH1LMNAPTPN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL8560324 | 0.82 | PPARG (0.47) | NCEH1LMNAPTPN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL8557408 | 0.82 | PPARG (0.47) | NCEH1LMNAPTPN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL9241012 | 0.77 | NCEH1 (0.46) | NCEH1RXFP1KMT2ALMNAPTPN1 | |
| SCHEMBL9241022 | 0.77 | NCEH1 (0.46) | NCEH1RXFP1KMT2ALMNAPTPN1 | |
| SCHEMBL8564030 | 0.69 | GRIK1 (0.48) | KMT2ALMNAKDM4ESLC1A3SLC1A2 | |
| SCHEMBL8564033 | 0.69 | GRIK1 (0.48) | KMT2ALMNAKDM4ESLC1A3SLC1A2 | |
| SCHEMBL8559718 | 0.68 | PPARG (0.64) | KMT2APTPN1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8564894 | 0.68 | PPARG (0.64) | KMT2APTPN1SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843997-A | Excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 1998-12-01 | — | — | US | disclosed |
| US-5576323-A | CENTRAL NERVOUS SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1996-11-19 | — | — | US | disclosed |