Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | FKBP4 | Q02790 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8898559 | 1.00 | TSHR (0.38) | TSHRFKBP4CYP2C19FKBP1A | |
| SCHEMBL8559303 | 1.00 | TSHR (0.38) | TSHRFKBP4CYP2C19FKBP1A | |
| SCHEMBL11353898 | 0.79 | TSHR (0.43) | TSHRFKBP4CYP2C19 | |
| SCHEMBL25632761 | 0.72 | TSHR (0.31) | TSHR | |
| SCHEMBL22481540 | 0.70 | HSD11B1 (0.33) | — | |
| SCHEMBL13824695 | 0.70 | TSHR (0.41) | TSHRFKBP4FKBP1A | |
| SCHEMBL8011001 | 0.70 | — | — | |
| SCHEMBL26008058 | 0.70 | — | — | |
| SCHEMBL7516937 | 0.70 | MEN1 (0.37) | — | |
| SCHEMBL11353706 | 0.69 | FKBP4 (0.40) | TSHRFKBP4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804577-A | ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1998-09-08 | — | — | US | disclosed |