Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL9314114 | 1.00 | — | — | |
| Dioxane SCHEMBL20141462 | 0.95 | TTR (0.55) | TTRTSHRLMNAPOLBSMN1; SMN2 | |
| Butane SCHEMBL28165623 | 0.95 | — | — | |
| Butane SCHEMBL28329516 | 0.86 | — | — | |
| Oxirane SCHEMBL2842413 | 0.84 | — | — | |
| Dioxane SCHEMBL6826845 | 0.82 | TSHR (0.58) | TTRTSHRLMNAPOLBSMN1; SMN2 | |
| Pentane SCHEMBL27681570 | 0.82 | — | — | |
| Hexane SCHEMBL5207457 | 0.82 | — | — | |
| Oxirane SCHEMBL27733054 | 0.80 | — | — | |
| Tetrahydrofuran SCHEMBL6854578 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0595458-B1 | Novel thiomarinol derivatives, and processes for their preparation | SANKYO CO (JP) | 1998-11-25 | — | — | EP | claimed |
| EP-0595458-A1 | Novel thiomarinol derivatives, and processes for their preparation | SANKYO COMPANY LIMITED (JP) | 1994-05-04 | — | — | EP | claimed |
| US-8796474-B1 | Macrolide compounds and methods and intermediates useful for their preparation | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2014-08-05 | — | — | US | disclosed |
| EP-0595458-B1 | Novel thiomarinol derivatives, and processes for their preparation | SANKYO CO (JP) | 1998-11-25 | — | — | EP | disclosed |
| US-5399711-A | Bactericides, antimycoplasma agent, from Alteromonas | SANKYO COMPANY, LIMITED (JP) | 1995-03-21 | — | — | US | disclosed |
| EP-0595458-A1 | Novel thiomarinol derivatives, and processes for their preparation | SANKYO COMPANY LIMITED (JP) | 1994-05-04 | — | — | EP | disclosed |