Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL8559403 | 0.95 | TTR (0.46) | TTRTSHRLMNASMN1; SMN2POLB | |
| Butane SCHEMBL9314114 | 0.95 | — | — | |
| Butane SCHEMBL28165623 | 0.91 | — | — | |
| Pentane SCHEMBL27681570 | 0.87 | — | — | |
| Dioxane SCHEMBL6826845 | 0.87 | TSHR (0.58) | TTRTSHRLMNAALDH1A1MEN1 | |
| Dioxane SCHEMBL1463561 | 0.84 | TSHR (0.54) | TTRTSHRLMNAALDH1A1MEN1 | |
| Tetrahydrofuran SCHEMBL6854578 | 0.84 | — | — | |
| Butane SCHEMBL28329516 | 0.82 | — | — | |
| Butane SCHEMBL20141461 | 0.81 | ALDH1A1 (0.57) | TTRTSHRLMNAALDH1A1 | |
| Heptane SCHEMBL1803195 | 0.81 | TSHR (0.57) | TTRTSHRLMNAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311929-A | SECO Macrocyclic lactone compounds | 菲德尔塔公司 | 2019-02-05 | — | — | CN | disclosed |
| CN-104231082-B | The amino acid sequence for RANK-L for treating bone disease and illness and the polypeptide including it | 埃博灵克斯股份有限公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-103246163-B | Colored curable resin composition | 住友化学株式会社 | 2018-06-12 | — | — | CN | disclosed |
| WO-2018089786-A1 | ATG7 INHIBITORS AND THE USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| CN-107079924-A | Enhanced antimicrobial superacid composite and the method used at reduced temperatures in sterile cleaning | 艺康美国股份有限公司 | 2017-08-22 | — | — | CN | disclosed |
| CN-103826453-B | Enhanced antimicrobial peracid compositions and methods for use in aseptic cleaning at reduced temperatures | 艺康美国股份有限公司 | 2017-04-26 | — | — | CN | disclosed |
| CN-104854110-B | Olanzapine haptens | 詹森药业有限公司 | 2016-12-28 | — | — | CN | disclosed |
| CN-103209970-B | In-situ chemical luminescence substrate and mensuration | 生命科技公司 | 2016-08-24 | — | — | CN | disclosed |