Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.32 |
| ▸ | GCGR | P47871 | 14/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.31 |
| ▸ | GCG | P01275 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8174692 | 0.82 | F2 (0.42) | — | |
| SCHEMBL8169955 | 0.80 | CTSK (0.36) | CA12GPR88 | |
| SCHEMBL8162689 | 0.76 | HSD17B10 (0.38) | — | |
| SCHEMBL4672469 | 0.75 | CA12 (0.36) | CA12CA9GCGR | |
| SCHEMBL8169531 | 0.73 | F2 (0.40) | — | |
| SCHEMBL1432767 | 0.73 | AOC3 (0.39) | GPR88 | |
| SCHEMBL11005234 | 0.69 | HRH3 (0.39) | CA12CA9 | |
| SCHEMBL9030206 | 0.68 | PRMT1 (0.32) | — | |
| SCHEMBL6003373 | 0.67 | POLB (0.42) | — | |
| SCHEMBL9572839 | 0.66 | PPARG (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832076-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-04-01 | — | — | EP | disclosed |
| EP-0730590-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-09-11 | — | — | EP | disclosed |