⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL27880395 | 0.87 | TP53 (0.42) | — | |
| Oxalic Acid SCHEMBL30172480 | 0.84 | TP53 (0.40) | — | |
| SCHEMBL4407513 | 0.83 | — | — | |
| SCHEMBL10711225 | 0.80 | — | — | |
| SCHEMBL8031153 | 0.78 | — | — | |
| SCHEMBL20544013 | 0.78 | — | — | |
| SCHEMBL306919 | 0.78 | — | — | |
| SCHEMBL204394 | 0.75 | — | — | |
| SCHEMBL4601424 | 0.75 | — | — | |
| SCHEMBL31418728 | 0.75 | LMNA (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115569234-A | Basalt fiber pipe sleeve for prosthetic socket and preparation method thereof | 北京连续玄武岩纤维科技有限公司 | 2023-01-06 | — | — | CN | disclosed |
| EP-0858452-A1 | THIAZOLE DERIVATIVE AS PROTEIN KINASE C INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-08-19 | — | — | EP | disclosed |
| WO-1998004536-A1 | THIAZOLE DERIVATIVE AS PROTEIN KINASE C INHIBITORS | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1998-02-05 | — | — | WO | disclosed |