Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2184286 | 1.00 | GAA (0.39) | GAAEPHX1MAOAMAOBEPHX2 | |
| SCHEMBL2182196 | 1.00 | GAA (0.39) | GAAEPHX1MAOAMAOBEPHX2 | |
| SCHEMBL8559648 | 1.00 | GAA (0.39) | GAAEPHX1MAOAMAOBEPHX2 | |
| SCHEMBL8559748 | 1.00 | GAA (0.39) | GAAEPHX1MAOAMAOBEPHX2 | |
| SCHEMBL8564507 | 1.00 | GAA (0.39) | GAAEPHX1MAOAMAOBEPHX2 | |
| SCHEMBL2182132 | 0.89 | ALDH1A1 (0.42) | GAAEPHX1MAOAMAOBEPHX2 | |
| SCHEMBL7809493 | 0.88 | GAA (0.39) | GAAEPHX1MAOAMAOBEPHX2 | |
| SCHEMBL21725322 | 0.88 | GAA (0.39) | GAAEPHX1MAOAMAOBEPHX2 | |
| SCHEMBL19098269 | 0.88 | GAA (0.39) | GAAEPHX1MAOAMAOBEPHX2 | |
| SCHEMBL19098270 | 0.88 | GAA (0.39) | GAAEPHX1MAOAMAOBEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837868-A | REACTION OF DIHYDROXY OLEFINS IN A MULTISTAGE PROCESS ARYL METHYLAMINE TO FORM PYRROLIDINE INTERMEDIATE | ABBOTT LABORATORIES (US) | 1998-11-17 | — | — | US | disclosed |
| US-5703244-A | CYCLIZATION OF DIHYDROXY OLEFINS WITH TARTRATE ESTER IN PRESENCE OF TITANIUM ISOPROPOXIDE AND TERT-BUTYL HYDROPEROXIDE | ABBOTT LABORATORIES (US) | 1997-12-30 | — | — | US | disclosed |
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | disclosed |