Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 5/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560578 | 0.88 | DRD2 (0.42) | CA1CA2CA7CA9CA14 | |
| SCHEMBL27498312 | 0.87 | HTR2A (0.44) | CA1CA2CA7CA9CA14 | |
| Hydrochloric Acid SCHEMBL1022841 | 0.83 | CA1 (0.43) | CA1CA2CA7CA9CA14 | |
| SCHEMBL5161528 | 0.80 | TSHR (0.54) | TSHR | |
| SCHEMBL27527951 | 0.78 | HTR2A (0.46) | KDM1AADRB1SLC6A9 | |
| SCHEMBL4573507 | 0.74 | TSHR (0.62) | CA1CA2CA7CA9CA14 | |
| SCHEMBL14267384 | 0.73 | CA1 (0.51) | CA1CA2CA7CA9CA14 | |
| SCHEMBL7124159 | 0.72 | CA1 (0.46) | CA1CA2CA7CA9CA14 | |
| SCHEMBL7199949 | 0.71 | CA1 (0.52) | CA1CA2CA7CA9CA14 | |
| Hydrochloric Acid SCHEMBL3534709 | 0.71 | CA1 (0.45) | CA1CA2CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1240448-A | Method of preparation of physostigmine carbamate derivatives from eseproline ethers | HOECHST MARION ROUSSEL INC (US) | 2000-01-05 | — | — | CN | claimed |
| CN-1235607-A | Preparation of physostigmine carbamate derivatives from eseretholes | HOECHST MARION ROUSSEL INC (US) | 1999-11-17 | — | — | CN | claimed |
| CN-1240448-A | Method of preparation of physostigmine carbamate derivatives from eseproline ethers | HOECHST MARION ROUSSEL INC (US) | 2000-01-05 | — | — | CN | disclosed |
| CN-1235607-A | Preparation of physostigmine carbamate derivatives from eseretholes | HOECHST MARION ROUSSEL INC (US) | 1999-11-17 | — | — | CN | disclosed |
| EP-0538248-B1 | TETRAHYDROISOQUINOLINYLCARBAMATES OF 1,2,3,3A,8,8A-HEXAHYDRO-1,3A,8-TRIMETHYLPYRROLO [2,3-B]INDOLE | HOECHST MARION ROUSSEL INC (US) | 1998-02-11 | — | — | EP | disclosed |