Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | ADH1B | P00325 | 3/20 | 0.33 |
| ▸ | ADH1C | P00326 | 3/20 | 0.33 |
| ▸ | ADH1A | P07327 | 3/20 | 0.33 |
| ▸ | ADH7 | P40394 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
| ▸ | ADH4 | P08319 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7498215 | 0.77 | EPHX1 (0.39) | TSHRSMN1; SMN2ATMCTSKCYP3A4 | |
| SCHEMBL14820781 | 0.77 | — | — | |
| SCHEMBL6931736 | 0.77 | — | — | |
| SCHEMBL9053284 | 0.77 | — | — | |
| SCHEMBL11361880 | 0.75 | — | — | |
| SCHEMBL11361898 | 0.75 | — | — | |
| SCHEMBL9388691 | 0.75 | ALDH1A1 (0.36) | DNM1ALDH1A1 | |
| SCHEMBL15003145 | 0.75 | TSHR (0.35) | TSHRSMN1; SMN2HPGD | |
| SCHEMBL2215390 | 0.75 | TSHR (0.39) | TSHRSMN1; SMN2ATMADH1BADH1C | |
| SCHEMBL23215822 | 0.74 | TSHR (0.35) | TSHRSMN1; SMN2ATMADH1BADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107602497-A | A kind of preparation method of the Wan isoxazoles of 3 amino 5 | 浦拉司科技（上海）有限责任公司 | 2018-01-19 | — | — | CN | disclosed |
| EP-0858452-A1 | THIAZOLE DERIVATIVE AS PROTEIN KINASE C INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-08-19 | — | — | EP | disclosed |
| WO-1998004536-A1 | THIAZOLE DERIVATIVE AS PROTEIN KINASE C INHIBITORS | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1998-02-05 | — | — | WO | disclosed |
| US-4277610-A | Synthesis of 2,6,10-trimethyl-undecan-1-ol | HOFFMANN-LA ROCHE INC. (US) | 1981-07-07 | — | — | US | disclosed |
| US-4191842-A | Protected alcohols | HOFFMANN-LA ROCHE INC. (US) | 1980-03-04 | — | — | US | disclosed |
| US-4180682-A | Unsaturated alcohols having an ether protected group | HOFFMANN-LA ROCHE INC. (US) | 1979-12-25 | — | — | US | disclosed |
| US-4172958-A | Ethers of 2,6,10-trimethyl-undecan-1-ols | HOFFMANN-LA ROCHE INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4169209-A | Ethers of 2,6-dimethyl-octane-1,8-diols | HOFFMANN-LA ROCHE INC. (US) | 1979-09-25 | — | — | US | disclosed |
| US-4163021-A | Synthesis of 2,6,10-trimethyl-undecan-1-ol | HOFFMANN-LA ROCHE INC. (US) | 1979-07-31 | — | — | US | disclosed |
| US-4151205-A | Synthesis of vitamin E | HOFFMAN-LA ROCHE INC. (US) | 1979-04-24 | — | — | US | disclosed |
| US-4140723-A | Intermediate compounds for producing vitamin E | HOFFMANN-LA ROCHE INC. (US) | 1979-02-20 | — | — | US | disclosed |
| US-4140702-A | Process for producing vitamin E intermediate compounds | HOFFMANN-LA ROCHE INC. (US) | 1979-02-20 | — | — | US | disclosed |
| US-4111961-A | Silicon ester of carboxylic acid | HOFFMANN-LA ROCHE INC. (US) | 1978-09-05 | — | — | US | disclosed |
| US-4051153-A | Intermediates in the synthesis of vitamin E | HOFFMANN-LA ROCHE INC. (US) | 1977-09-27 | — | — | US | disclosed |
| US-4041058-A | Synthesis of 2,6,10-trimethyl-undecan-1-ol | HOFFMANN-LA ROCHE INC. (US) | 1977-08-09 | — | — | US | disclosed |