Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11087194 | 1.00 | HPGD (0.53) | HPGDHSD17B10TSHRMAPK1KMT2A | |
| SCHEMBL7171833 | 0.84 | KMT2A (0.62) | HSD17B10KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL6823137 | 0.84 | KMT2A (0.62) | HSD17B10KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL21130380 | 0.81 | KMT2A (0.42) | HSD17B10KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL10429393 | 0.79 | GABRA1 (0.50) | HSD17B10MAPK1KMT2AMEN1ALDH1A1 | |
| SCHEMBL21629335 | 0.79 | KMT2A (0.40) | HSD17B10KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL21629336 | 0.79 | KMT2A (0.40) | HSD17B10KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL10889472 | 0.78 | HPGD (0.42) | HPGDHSD17B10TSHRMAPK1KMT2A | |
| SCHEMBL11371187 | 0.78 | SIRT2 (0.43) | HSD17B10KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL3297831 | 0.77 | GABRA1 (0.47) | HSD17B10MAPK1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454622-B1 | Alkenyl substituted stabilizers | CIBA GEIGY AG (CH) | 1999-10-13 | — | — | EP | disclosed |
| EP-0454622-A1 | Alkenyl substituted stabilizers | CIBA-GEIGY AG (CH) | 1991-10-30 | — | — | EP | disclosed |
| US-5045583-A | O-alkenyl substituted hydroxylamine stabilizers | CIBA-GEIGY CORPORATION (US) | 1991-09-03 | — | — | US | disclosed |
| US-4696964-A | HEAT RESISTANCE, OXIDATION RESISTANCE | CIBA-GEIGY CORPORATION (US) | 1987-09-29 | — | — | US | disclosed |
| EP-0121701-A1 | Process for the production of o-substituted oximes | ALLIED CORPORATION (US) | 1984-10-17 | — | — | EP | disclosed |