Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | RXRA | P19793 | 11/20 | 0.56 |
| ▸ | RXRB | P28702 | 9/20 | 0.56 |
| ▸ | RXRG | P48443 | 5/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 8/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | NPY1R | P25929 | 1/20 | 0.51 |
| ▸ | NPY2R | P49146 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.49 |
| ▸ | C5 | P01031 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555806 | 0.94 | RXRA (0.52) | KDM4EHPGDALDH1A1RXRARXRB | |
| SCHEMBL8556331 | 0.92 | KDM4E (0.56) | KDM4EHPGDALDH1A1RXRARXRB | |
| SCHEMBL8555035 | 0.90 | NR4A2 (0.48) | KDM4EHPGDALDH1A1RXRARXRB | |
| SCHEMBL8560771 | 0.90 | RXRA (0.55) | KDM4EHPGDALDH1A1RXRARXRB | |
| SCHEMBL8560614 | 0.86 | RXRA (0.52) | KDM4EHPGDALDH1A1RXRARXRB | |
| SCHEMBL8556748 | 0.86 | RXRA (0.67) | KDM4EHPGDRXRARXRBRXRG | |
| SCHEMBL6309920 | 0.85 | NR4A2 (0.59) | KDM4EHPGDRXRARXRBRXRG | |
| SCHEMBL7506843 | 0.85 | KDM4E (0.62) | KDM4EHPGDALDH1A1RXRARXRB | |
| SCHEMBL7506747 | 0.85 | KDM4E (0.62) | KDM4EHPGDALDH1A1RXRARXRB | |
| SCHEMBL8560570 | 0.84 | RXRA (0.53) | KDM4EHPGDRXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |