Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 8/20 | 0.56 |
| ▸ | AVPR1A | P37288 | 8/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559508 | 0.94 | AVPR2 (0.59) | AVPR2AVPR1ACYP2C9 | |
| SCHEMBL8558900 | 0.91 | AVPR2 (0.65) | AVPR2AVPR1ACYP2C9 | |
| SCHEMBL8558733 | 0.91 | AVPR2 (0.65) | AVPR2AVPR1A | |
| SCHEMBL8558428 | 0.87 | AVPR2 (0.57) | AVPR2AVPR1A | |
| SCHEMBL8562591 | 0.86 | AVPR2 (0.64) | AVPR2AVPR1ACYP2C9 | |
| SCHEMBL8561780 | 0.86 | AVPR2 (0.54) | AVPR2AVPR1A | |
| SCHEMBL8556841 | 0.86 | AVPR2 (0.65) | AVPR2AVPR1A | |
| SCHEMBL8562554 | 0.86 | AVPR2 (0.73) | AVPR2AVPR1A | |
| SCHEMBL8559571 | 0.86 | AVPR2 (0.62) | AVPR2AVPR1A | |
| SCHEMBL8556807 | 0.85 | AVPR2 (0.56) | AVPR2AVPR1ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |