Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 6/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.35 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.32 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | NPY1R | P25929 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | HK2 | P52789 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1031741 | 1.00 | PAX8 (0.45) | PAX8PDCD1LG2CD274DPP4DPP8 | |
| SCHEMBL18888162 | 0.91 | PAX8 (0.40) | PAX8PDCD1LG2CD274DPP4DPP8 | |
| SCHEMBL10067240 | 0.84 | DPP9 (0.44) | PAX8DPP4DPP8DPP9SLC15A1 | |
| SCHEMBL2739683 | 0.84 | DPP9 (0.44) | PAX8DPP4DPP8DPP9SLC15A1 | |
| SCHEMBL2739682 | 0.84 | DPP9 (0.44) | PAX8DPP4DPP8DPP9SLC15A1 | |
| SCHEMBL25587465 | 0.82 | SLC7A5 (0.47) | PAX8KDM4E | |
| SCHEMBL16421636 | 0.82 | PAX8 (0.37) | PAX8DPP4DPP8DPP9SLC15A1 | |
| SCHEMBL1035793 | 0.81 | PAX8 (0.42) | PAX8PDCD1LG2CD274DPP4DPP8 | |
| SCHEMBL13333785 | 0.79 | PAX8 (0.45) | PAX8PDCD1LG2CD274DPP4DPP8 | |
| SCHEMBL19650493 | 0.79 | PAX8 (0.40) | PAX8ALDH1A1CYP3A4CYP2C9HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819135-A1 | SUGAR-MODIFIED CYTOSTATICS | BAYER AG (DE) | 1998-01-21 | — | — | EP | disclosed |
| WO-1996031532-A1 | SUGAR-MODIFIED CYTOSTATICS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-10-10 | — | — | WO | disclosed |