Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | GPR183 | P32249 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
| ▸ | ITGAL | P20701 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561189 | 1.00 | KDM4E (0.36) | KDM4EALDH1A1NPC1RAB9APOLB | |
| SCHEMBL7470956 | 1.00 | KDM4E (0.36) | KDM4EALDH1A1NPC1RAB9APOLB | |
| SCHEMBL7467380 | 0.93 | TP53 (0.35) | KDM4EALDH1A1NPC1RAB9APOLB | |
| SCHEMBL7467375 | 0.93 | TP53 (0.35) | KDM4EALDH1A1NPC1RAB9APOLB | |
| Hydrochloric Acid SCHEMBL7468011 | 0.92 | TP53 (0.34) | KDM4EALDH1A1NPC1RAB9APOLB | |
| SCHEMBL7466065 | 0.86 | LMNA (0.42) | KDM4EALDH1A1NPC1RAB9APOLB | |
| SCHEMBL7469785 | 0.82 | KDM4E (0.40) | KDM4EALDH1A1POLBLMNATP53 | |
| SCHEMBL7469782 | 0.82 | KDM4E (0.40) | KDM4EALDH1A1POLBLMNATP53 | |
| SCHEMBL7471916 | 0.82 | BRD4 (0.36) | KDM4EALDH1A1NPC1RAB9APOLB | |
| SCHEMBL7471921 | 0.82 | BRD4 (0.36) | KDM4EALDH1A1NPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858452-A1 | THIAZOLE DERIVATIVE AS PROTEIN KINASE C INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-08-19 | — | — | EP | disclosed |
| WO-1998004536-A1 | THIAZOLE DERIVATIVE AS PROTEIN KINASE C INHIBITORS | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1998-02-05 | — | — | WO | disclosed |