Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.47 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.47 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557693 | 0.96 | EPHX2 (0.56) | HTTEPHX2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL8174680 | 0.91 | ALDH1A1 (0.51) | HTTEPHX2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL24180428 | 0.88 | HTT (0.60) | HTTEPHX2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL20362125 | 0.84 | HTT (0.56) | HTTEPHX2L3MBTL1TPSAB1TPSD1 | |
| SCHEMBL21171925 | 0.84 | HTT (0.67) | HTTL3MBTL1LMNASMN1; SMN2TGM2 | |
| SCHEMBL24486949 | 0.84 | HTT (0.67) | HTTL3MBTL1KMT2AMEN1LMNA | |
| SCHEMBL12409527 | 0.84 | HTT (0.80) | HTTEPHX2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL13243335 | 0.83 | HTT (0.54) | HTTALDH1A1MAPK1L3MBTL1KMT2A | |
| Hydrochloric Acid SCHEMBL9352205 | 0.82 | MEN1 (0.46) | HTTEPHX2ALDH1A1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9352193 | 0.82 | MEN1 (0.46) | HTTEPHX2ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832076-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-04-01 | — | — | EP | disclosed |