Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 4/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7509608 | 1.00 | SIGMAR1 (0.40) | SIGMAR1EPHX1BRD4SLC6A2SLC6A3 | |
| SCHEMBL4457615 | 0.86 | SLC6A2 (0.39) | BRD4SLC6A2SLC6A3SLC6A4ADRB2 | |
| Hydrochloric Acid SCHEMBL10511614 | 0.84 | SLC6A2 (0.38) | BRD4SLC6A2SLC6A3SLC6A4ADRB2 | |
| SCHEMBL11652607 | 0.84 | SLC6A2 (0.40) | EPHX1SLC6A2SLC6A3SLC6A4ADRB2 | |
| SCHEMBL28142918 | 0.81 | SLC6A2 (0.34) | EPHX1BRD4SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL4423889 | 0.81 | EPHX1 (0.60) | EPHX1SLC6A2SLC6A3SLC6A4ADRB2 | |
| SCHEMBL8657970 | 0.81 | EPHX1 (0.60) | EPHX1SLC6A2SLC6A3SLC6A4ADRB2 | |
| SCHEMBL16652362 | 0.81 | EPHX1 (0.60) | EPHX1SLC6A2SLC6A3SLC6A4ADRB2 | |
| SCHEMBL17649948 | 0.81 | EPHX1 (0.60) | EPHX1SLC6A2SLC6A3SLC6A4ADRB2 | |
| SCHEMBL8661751 | 0.81 | EPHX1 (0.60) | EPHX1SLC6A2SLC6A3SLC6A4ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575954-B1 | Aminoalkylcarbamic esters of eseroline suitable for use as cholinesterase acitivity inhibitors and relative preparation process | MEDIOLANUM FARMACEUTICI SRL (IT) | 1998-09-02 | — | — | EP | disclosed |
| US-5424451-A | Used as cholinesterase activity inhibitors | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1995-06-13 | — | — | US | disclosed |
| US-5302593-A | Aminoalkylcarbamic esters of eseroline suitable for use as chlorinesterase activity inhibitors | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1994-04-12 | — | — | US | disclosed |
| EP-0575954-A1 | Aminoalkylcarbamic esters of eseroline suitable for use as cholinesterase acitivity inhibitors and relative preparation process | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1993-12-29 | — | — | EP | disclosed |