Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 19/20 | 0.52 |
| ▸ | AGTR2 | P50052 | 19/20 | 0.52 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560538 | 0.92 | AGTR1 (0.53) | AGTR1AGTR2LTB4R2 | |
| SCHEMBL8563659 | 0.92 | AGTR1 (0.59) | AGTR1AGTR2 | |
| SCHEMBL8563660 | 0.85 | AGTR1 (0.61) | AGTR1AGTR2 | |
| SCHEMBL8563244 | 0.82 | AGTR1 (0.56) | AGTR1AGTR2LTB4R2 | |
| SCHEMBL6607280 | 0.78 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL6606990 | 0.76 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL9590460 | 0.76 | AGTR1 (0.60) | AGTR1AGTR2 | |
| SCHEMBL9256905 | 0.75 | AGTR1 (0.59) | AGTR1AGTR2 | |
| SCHEMBL9590184 | 0.75 | AGTR1 (0.62) | AGTR1AGTR2 | |
| SCHEMBL9589685 | 0.74 | AGTR1 (0.59) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0603001-B1 | Biphenyl derivatives, their preparation and their use for the treatment of hypertension and cardiac disease | SANKYO CO (JP) | 1998-08-26 | — | — | EP | disclosed |
| US-5459148-A | Cardiovascular disorders | SANKYO COMPANY, LIMITED (JP) | 1995-10-17 | — | — | US | disclosed |