Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MGMT | P16455 | 1/20 | 0.31 |
| ▸ | NPY1R | P25929 | 1/20 | 0.30 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28232725 | 0.80 | MEN1 (0.37) | MEN1USP2KMT2AKEAP1NFE2L2 | |
| SCHEMBL28232714 | 0.76 | CDK2 (0.40) | MEN1USP2KMT2AKEAP1NFE2L2 | |
| SCHEMBL8563511 | 0.74 | MKNK1 (0.36) | MEN1USP2KMT2AKEAP1NFE2L2 | |
| SCHEMBL8561310 | 0.73 | KDM1A (0.34) | MEN1KMT2AMAPTKDM4ELMNA | |
| SCHEMBL28802588 | 0.72 | MEN1 (0.41) | MEN1USP2KMT2AKEAP1NFE2L2 | |
| SCHEMBL18397997 | 0.71 | MEN1 (0.35) | MEN1USP2KMT2AKEAP1NFE2L2 | |
| SCHEMBL3688848 | 0.71 | MAPT (0.47) | MEN1USP2KMT2AKEAP1NFE2L2 | |
| SCHEMBL31302371 | 0.70 | NPC1 (0.34) | MAPTHTTKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL18486948 | 0.70 | KMT2A (0.42) | MEN1USP2KMT2AKEAP1NFE2L2 | |
| SCHEMBL8561095 | 0.70 | MEN1 (0.42) | MEN1USP2KMT2AKEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |