Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | CALML3 | P27482 | 1/20 | 0.47 |
| ▸ | SDHA | P31040 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 7/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7520010 | 0.83 | MAOA (0.47) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL8562221 | 0.83 | MAOA (0.47) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL9550280 | 0.81 | GRM2 (0.56) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL13298924 | 0.81 | MAOA (0.61) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL7026010 | 0.80 | MAOA (0.44) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL6399424 | 0.80 | MAOA (0.51) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL6398607 | 0.80 | MAOA (0.51) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL6335767 | 0.80 | MAOA (0.50) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL6335763 | 0.80 | MAOA (0.50) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL6348267 | 0.80 | MAOA (0.50) | MAOAMAOBLMNAPTGS1CALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882042-A1 | ANTIBIOTIC OXAZOLIDINONE DERIVATIVES | AstraZeneca UK Limited (GB) | 1998-12-09 | — | — | EP | disclosed |
| WO-1997030995-A1 | ANTIBIOTIC OXAZOLIDINONE DERIVATIVES | ZENECA LIMITED (GB) | 1997-08-28 | — | — | WO | disclosed |