Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.37 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PYGM | P11217 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11815477 | 0.77 | POLB (0.51) | CA1CA2LMNASQORKMT2A | |
| SCHEMBL8561169 | 0.77 | TYMP (0.38) | CA1CA2KMT2APOLBGRIA1 | |
| SCHEMBL8559503 | 0.75 | CA1 (1.00) | CA1CA2TDP1LMNAALDH1A1 | |
| SCHEMBL35345 | 0.71 | TDP1 (0.57) | CA1CA2TDP1LMNAGAA | |
| SCHEMBL11144152 | 0.69 | TDP1 (0.55) | CA1CA2TDP1LMNAGAA | |
| SCHEMBL26044336 | 0.68 | TDP1 (0.53) | CA1CA2TDP1LMNAGAA | |
| SCHEMBL400005 | 0.67 | TDP1 (1.00) | CA1CA2TDP1GAASQOR | |
| SCHEMBL22114444 | 0.67 | TDP1 (0.57) | CA1CA2TDP1GAASQOR | |
| SCHEMBL28179393 | 0.67 | TDP1 (0.57) | CA1CA2TDP1GAASQOR | |
| SCHEMBL65891 | 0.64 | TDP1 (0.53) | CA1CA2TDP1GAASQOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877022-A1 | Synthesis of the sulfonylpyrimidine derivatives with anticancer activity | Herbos d.d. (HR) | 1998-11-11 | — | — | EP | claimed |
| EP-0877022-A1 | Synthesis of the sulfonylpyrimidine derivatives with anticancer activity | Herbos d.d. (HR) | 1998-11-11 | — | — | EP | disclosed |