Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 1.00 |
| ▸ | CA2 | P00918 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | UBE2N | P61088 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5695322 | 0.86 | CA1 (0.75) | CA1CA2LMNAPOLBALDH1A1 | |
| SCHEMBL7013629 | 0.82 | CA1 (0.69) | CA1CA2LMNAPOLBMAPT | |
| SCHEMBL8561394 | 0.82 | CA1 (0.69) | CA1CA2LMNAPOLBMAPT | |
| SCHEMBL8560725 | 0.75 | CA1 (0.59) | CA1CA2LMNAPOLBALDH1A1 | |
| SCHEMBL16865327 | 0.74 | CA1 (0.58) | CA1CA2LMNAPOLBALDH1A1 | |
| SCHEMBL7021931 | 0.73 | CA1 (0.57) | CA1CA2POLBALDH1A1MAPT | |
| SCHEMBL11817179 | 0.73 | POLB (0.64) | CA1CA2LMNAPOLBMMP2 | |
| SCHEMBL18952030 | 0.72 | CA1 (0.56) | CA1CA2POLBALDH1A1MAPT | |
| SCHEMBL7010844 | 0.71 | CA1 (0.55) | CA1CA2LMNAPOLBALDH1A1 | |
| SCHEMBL15069632 | 0.71 | CA1 (0.54) | CA1CA2LMNAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877022-A1 | Synthesis of the sulfonylpyrimidine derivatives with anticancer activity | Herbos d.d. (HR) | 1998-11-11 | — | — | EP | claimed |
| EP-0877022-A1 | Synthesis of the sulfonylpyrimidine derivatives with anticancer activity | Herbos d.d. (HR) | 1998-11-11 | — | — | EP | disclosed |