SCHEMBL856078

SCHEMBL856078

CCOC(=O)C(CC)C(C)=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.48
LMNA P02545 1/20 0.48
HSD17B10 Q99714 1/20 0.48
GAA P10253 4/20 0.40
ALOX15 P16050 1/20 0.40
MGAM O43451 1/20 0.40
SI P14410 1/20 0.40
MGAM2 Q2M2H8 1/20 0.40
SOAT1 P35610 1/20 0.40
HPGD P15428 1/20 0.40
RECQL P46063 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
KDM4E B2RXH2 2/20 0.39
MAPT P10636 2/20 0.39
HTT P42858 1/20 0.39
TDP1 Q9NUW8 3/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
TRPA1 O75762 1/20 0.37
MMP8 P22894 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28474376 1.00 ALDH1A1 (0.48) ALDH1A1LMNAHSD17B10GAAALOX15
SCHEMBL29049226 0.98 ALDH1A1 (0.46) ALDH1A1LMNAHSD17B10GAAALOX15
SCHEMBL28368887 0.98 ALDH1A1 (0.46) ALDH1A1LMNAHSD17B10GAAALOX15
SCHEMBL17685839 0.98 ALDH1A1 (0.46) ALDH1A1LMNAHSD17B10GAAALOX15
Propane SCHEMBL28283403 0.98 ALDH1A1 (0.46) ALDH1A1LMNAHSD17B10GAAALOX15
SCHEMBL27604414 0.95 ALDH1A1 (0.44) ALDH1A1LMNAHSD17B10GAAALOX15
SCHEMBL27604320 0.93 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10GAAALOX15
SCHEMBL27457908 0.93 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10GAAALOX15
Dimethylamine SCHEMBL10870439 0.93 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10GAAALOX15
SCHEMBL5150133 0.93 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10GAAALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 991 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240306688-A1 METHOD OF MITIGATING OFF-ODORS GIVAUDAN SA (CH) 2024-09-19 US claimed
EP-4391827-A1 METHOD OF MITIGATING OFF-ODORS Givaudan SA (CH) 2024-07-03 EP claimed
CN-117897055-A Method for reducing abnormal odor 奇华顿股份有限公司 2024-04-16 CN claimed
CN-117486718-A Preparation method of 2-ethyl acetoacetate 三门峡奥科化工有限公司 2024-02-02 CN claimed
WO-2023025549-A1 METHOD OF MITIGATING OFF-ODORS GIVAUDAN SA (CH) 2023-03-02 WO claimed
CN-111253834-B Moisture-cured epoxy coating and preparation method thereof 滨州学院 2022-05-24 CN claimed
CN-111440174-B Pyridine amide compound and preparation method and application thereof 广州医科大学 2021-07-09 CN claimed
CN-111440174-A Pyridine amide compound and preparation method and application thereof 广州医科大学 2020-07-24 CN claimed
CN-111253834-A Moisture-curing epoxy coating and preparation method thereof 滨州学院 2020-06-09 CN claimed
US-20200079965-A1 POLYURETHANE COATING COMPOSITION SWIMC LLC (US) 2020-03-12 US claimed
CN-103965381-A Titanium tetrachloride co-initiation system, and method for preparing high-reaction-activity polyisobutylene by using it UNIV BEIJING CHEMICAL 2014-08-06 CN claimed
US-20110241175-A1 HARDMASK COMPOSITION FOR FORMING RESIST UNDERLAYER FILM, PROCESS FOR PRODUCING A SEMICONDUCTOR INTEGRATED CIRCUIT DEVICE, AND SEMICONDUCTOR INTEGRATED CIRCUIT DEVICE CHEIL INDUSTRIES, INC. (KR) 2011-10-06 US claimed
CN-102060754-A Method for preparing polysubstituted tetrahydropyridine UNIV NORTHWEST NORMAL 2011-05-18 CN claimed
CN-101798185-A Bullet-resistant glass and fireproof glass for insulating heat and resisting radiation, as well as compound glass thereof HAIBO HE 2010-08-11 CN claimed
WO-2010071255-A1 HARDMASK COMPOSITION WITH IMPROVED STORAGE STABILITY FOR FORMING RESIST UNDERLAYER FILM CHEIL INDUSTRIES INC. (KR) 2010-06-24 WO claimed
CN-100335456-C Method for preparing acyclic beta keto ester SHANGHAI INST OF CHEMICAL REAG (CN) 2007-09-05 CN claimed
CN-1176123-C Initiation system for preparing polyisobutene with reactive activity 北京化工大学 2004-11-17 CN claimed
CN-1323841-A Initiation system for preparing polyisobutene with reactive activity UNIV BEIJING CHEMICAL ENG (CN) 2001-11-28 CN claimed
EP-0180745-A1 Acylacetate and amidine intermediates for pyrimidone compounds, and their preparation YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1986-05-14 EP claimed
US-4333878-A MAKING 1,4-DIALKYLPYRROLE DIESTERS FROM 2-HYDROCARBOXY-1-NITROALKANE AND ENAMINE OF DIALKYL ACETONE DICARBOXYLATE ETHYL CORPORATION (US) 1982-06-08 US claimed