Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PTPRZ1 | P23471 | 2/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6637857 | 0.82 | HTT (0.45) | HTTKMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL507033 | 0.82 | MAOB (0.50) | HTTKMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL28724030 | 0.79 | HTT (0.48) | HTTKMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL5382500 | 0.78 | APP (0.53) | HTTKMT2ASMN1; SMN2MAPTPOLB | |
| SCHEMBL6944585 | 0.78 | HTT (0.47) | HTTKMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL3885645 | 0.78 | HTT (0.47) | HTTKMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL7769868 | 0.78 | HTT (0.47) | HTTKMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8560561 | 0.78 | PTPRZ1 (0.39) | SMN1; SMN2MAPTUSP2TSHRPTPRZ1 | |
| SCHEMBL1710061 | 0.78 | KMT2A (0.51) | HTTKMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL5384421 | 0.78 | HTT (0.50) | HTTKMT2ASMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0866793-A4 | — | — | 1998-10-07 | — | — | EP | disclosed |
| EP-0866793-A1 | NITROIMIDAZOLE ANTIBACTERIAL COMPOUNDS AND METHODS OF USE THEREOF | PATHOGENESIS CORPORATION (US) | 1998-09-30 | — | — | EP | disclosed |
| WO-1997001562-A1 | NITROIMIDAZOLE ANTIBACTERIAL COMPOUNDS AND METHODS OF USE THEREOF | PATHOGENESIS CORPORATION (US) | 1997-01-16 | — | — | WO | disclosed |